Latest from Agadir 24
Yahoo
24 minutes ago
- Business
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US stocks tend to gain around Fed's Jackson Hole summer conference, analysis shows
By Lewis Krauskopf NEW YORK (Reuters) -U.S. stocks have tended to fare well around the Federal Reserve's Jackson Hole gathering in August, according to a historical analysis from DataTrek Research, although the market has seen sizable moves in both directions in recent years. The Fed's annual Wyoming research conference is set for Thursday through Saturday, and Chair Jerome Powell's speech on Friday is expected to be the main event for markets. DataTrek looked at the benchmark S&P 500 in the five trading days before and after the Fed chair's speech since 2010. The index gained an average of 0.9% over the period, with the bulk after the speech. "This suggests that markets get incremental clarity from the chair's speech, which in turn boosts equity valuations," Nicholas Colas, DataTrek's co-founder, said in a research note. This year, the S&P 500 has slipped in the lead-up to the speech so far, Colas said in the note published early Tuesday. "This goes against the usual pattern, so we would not be surprised to see the index rally modestly through Thursday," he said. One notable exception to the trend was in 2022, when the index slumped 7.4% in the 10-day period. That year at Jackson Hole, Powell warned of slower growth as the Fed fought high inflation. The S&P 500 fell over 19% for the full year 2022 as the Fed raised interest rates. In 2023, the index gained 3.3% in the studied period. DataTrek noted the S&P 500 fell in 2013 and 2015 when Fed chairs Ben Bernanke and Janet Yellen did not attend the symposium. This year, investors are eager to see if Powell reinforces expectations of a central bank interest rate cut at its September 16-17 meeting. Recent weak labor market data bolstered those expectations. Fed Fund futures on Tuesday were pricing in an 84% chance of such a move, according to LSEG data.
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Myosin Therapeutics Awarded $4.5 Million NCI Bridge Grant to Advance Phase I Trial of MT-125 in Glioblastoma
JUPITER, Fla., Aug. 19, 2025 /PRNewswire/ -- Myosin Therapeutics, a biotechnology company developing novel therapies for aggressive cancers, today announced it has been awarded a $4.5M Phase IIB Bridge Award from the National Cancer Institute's (NCI) Small Business Innovation Research (SBIR) program. The funding will support Myosin Therapeutic's Phase I STAR-GBM dose escalation and expansion trial of MT-125, a first-in-class novel small molecule therapeutic being evaluated in patients with newly diagnosed, MGMT unmethylated glioblastoma. Glioblastoma remains among the most lethal cancers, with median survival measured in months. MT-125 targets non-muscle myosin II, a critical driver of tumor cell invasion, proliferation and treatment resistance, representing a novel therapeutic approach that is distinct from existing standards of care. The STAR-GBM trial will assess the safety, tolerability, and pharmacokinetics of MT-125 in this patient population with significant unmet need. Exploratory endpoints include measures of efficacy, including progression-free survival and overall survival. The NCI SBIR program is one of the most competitive federal funding mechanisms for cancer-focused innovation, providing support to small businesses with technologies that have strong scientific merit, commercial potential, and a clear path to clinical impact. Bridge Awards, which require that matching funds from private capital be raised first, are reserved for companies with promising, later-stage projects that have already demonstrated significant technical progress and the potential to attract substantial private investment. "The NCI Bridge Award was perfectly timed to support our STAR-GBM trial, for which patient enrollment is set to begin in November," said Dr. Courtney Miller, co-founder and CEO of Myosin Therapeutics. "It will enable us to generate the data needed to position the program for later-stage development, potential partnerships, and future expansion into a wider range of patients. Our ultimate goal is to deliver a transformative treatment option for patients who currently face limited or inadequate therapeutic choices." About Myosin TherapeuticsMyosin Therapeutics is a Jupiter, FL-based biotechnology company spun out of The Wertheim UF Scripps Institute (formerly Scripps Research, Florida). The company is focused on developing therapies for neuroscience and oncology indications using a platform that targets molecular nanomotor proteins. For more information, visit Contact: contact@ View original content to download multimedia: SOURCE Myosin Therapeutics Inc.
Yahoo
24 minutes ago
- Sport
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6 Chiefs won't practice on Tuesday; Steve Spagnuolo weighs in
Ahead of their practice at their home facility at the Truman Sports Complex on Tuesday, the Kansas City Chiefs listed six players who would not take the field due to injury or illness: linebacker Jack Cochrane (knee bruise), offensive lineman Ethan Driskell (appendectomy), safety Mike Edwards (hamstring), cornerback Nazeeh Johnson (shoulder), defensive tackle Omarr Norman-Lott (ankle) and wide receiver Jalen Royals (knee). Late Monday afternoon, Kansas City placed defensive end Felix Anudike-Uzomah on the Reserve/Injured list. Even though he is practicing, cornerback Kristian Fulton has yet to play in a preseason game as he recovers from offseason knee surgery. 'Well, the unknown is Kristian right now because we haven't had him out there,' said defensive coordinator Steve Spagnuolo. 'Jaylen [Watson] has missed some time, and now we've got [Johnson], who is a little dinged up. More than any group on the defense, that back end has to have a lot of continuity, and that comes with reps. So with a couple of different moving pieces, there's a little bit of concern there, so hopefully we can start to gel that together.' The Chiefs play their final game of the 2025 preseason against the Chicago Bears at home on Friday at 7:20 p.m. Arrowhead Time. Chiefs head coach Andy Reid has already confirmed that the starters will see playing time.
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24 minutes ago
- Sport
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Milan Lucic, 37, who last played in 2023, gets a tryout with the Blues
ST. LOUIS (AP) — The St. Louis Blues are bringing in 37-year-old forward Milan Lucic, who last played in 2023, for a tryout. Lucic was a member of the Boston Bruins' 2011 Stanley Cup championship team who also played for the Kings, Oilers and Flames before returning to the Bruins in 2023. He had two assists in four games that year before he took a puck off his ankle and went on long-term injured reserve. Three weeks later, police were called to Lucic's home by his wife, who told them he pulled her hair and tried to choke her. He was arrested on suspicion of assault and battery on a family member, but the charges were dropped when his wife declined to testify in court. Lucic entered the league's Player Assistance Program. The Blues say he has completed the program and has been reinstated by the NHL. Lucic has 233 goals, 353 assists and 1,301 penalty minutes in 17 NHL seasons. He had a career-high 32 goals with 30 assists in 2010-11 and assisted on the overtime winner in Game 7 of the first-round series against the Montreal Canadiens to help the Bruins win their most recent Stanley Cup title. ___ AP NHL:
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24 minutes ago
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USDA will heighten scrutiny for solar and wind projects on farms, but some may continue
By Leah Douglas and Nichola Groom WASHINGTON (Reuters) -The U.S. Department of Agriculture said on Tuesday it will heighten scrutiny of some solar and wind projects but stopped short of ending all agency support for clean energy projects on U.S. farms, according to a press release. The release came a day after Agriculture Secretary Brooke Rollins announced on X that her agency would no longer fund wind and solar on productive farmland. Rather, the agency said it will move away from funding larger renewable energy facilities, the Tuesday release said. Wind and solar projects will not be eligible for the agency's Rural Development Business and Industry Guaranteed Loan Program, the USDA said, and ground-mounted solar systems over 50 kilowatts and those that cannot document historical energy usage will not qualify for the Rural Energy for America Program Guaranteed Loan Program, according to the release. "USDA will ensure that American farmers, ranchers and producers utilizing wind and solar energy sources will install units that are right-sized for their facilities," the release said. The agency will also not allow the use of solar panels "manufactured by foreign adversaries" in USDA-funded projects, the release said. The USDA did not immediately respond to questions about whether smaller-scale projects are still eligible for agency support. Thomas Clark, director of marketing and communications for solar installation company Northstone Solar in Whitefish, Montana, said potential clients in his region had already been impacted by the USDA's pullback in project funding. "If you are trying to do a ground mount system on farmland, which a couple years ago would not have been an issue, now they don't want that to happen," Clark said. "And that just seems like you're sticking it to farmers that are trying to find ways to diversify their revenue and be able to stay in business." Rollins said in the release that prime farmland has been displaced by solar farms and the new investment guardrails are meant to keep farmland affordable. Yet data from the USDA shows that a very small amount of rural land is used for solar and wind projects and that most continues in agricultural production even after the projects are installed. Solve the daily Crossword
